Sonntag, 29. November 2009

Science review - 2009 week 45, 46 and 47

Nature vs. MAD:
Alberts about a better funding and better science
Alberts about PhD students lost in translation- with advice and hints - very cool:
A true letter about (IMHO) a huge problem in Science: Management
A super cool essay about academia, industry and skills:

Next generation sequencing:
Bing - not from Microsoft  - a framework to manage and evaluate data from NGS:

Binding promiscuity
An introduction by Nature:
and a cool paper:
and a paper I think is worth mentioning in this case:

Cloud computing in life sciences
Aligning and SNP calling in the cloud

Transcription factors and regulation
State of the Art:

RNA structure
TPP riboswitch - ligand free

Virus RNA packaging mediated by an RNA switch:

Ago silencing complex - from the Patel / Tuschl labs:

About the Antarctic Treaty - I hope it lasts as ice is melting and states can expand their greed for natural resources easily

Protein protein docking 
Knapp about selecting the most likely native docking decoy

The future of publication

Article-Level Metrics and the Evolution of Scientific Impact - PLoS Biology:
Public access is cool:

Drug discovery - book recommendations collected by Derek Lowe

really cool:
thanks Derek and contributors!

Mittwoch, 4. November 2009

It wasn't me!

Must have been somebody else. For instance: The genes in me :)

My bet: Berlusconi has some genes for bribing people what means he is not really responsible for his wrongdoings. So this is clearly a preparation for his upcoming trials.

Btw - the Italians have a gene that forces them to vote for incapable presidents. And the germans... well... ok...

Montag, 2. November 2009

Science review - 2009 week 44

Hwang moves on:

Nanotechnology and Russia:

Hunting is fun:

After the HIV vaccine revolution Nature did not like the hype:

A cool review about cance genome sequencing:

Sequencing and sorting - that's cool:

Structural Biology:
Fast strctural comparisons based on vectors:

and also:
Algorithms for the optimal superposition of proteins...:

A good starting point provided by the PLoS ONE for the SGC:

Systems Biology:
Kitano on networks and implications for drug design: