Science review - 2009 week 43

Glamour:
Nature about scientists talking journalists fooling them and how to react (and how not):
http://www.nature.com/nature/journal/v461/n7266/full/461848a.html


About the Polymath project, where a mathematic problem was solved using an open approach with wikis and so on - really cool:
http://www.nature.com/nature/journal/v461/n7266/full/461879a.html

and then you could also read an article about Google Wave and it's impact for science (accoring to the author - I am less sure there will be an impact).:
http://www.nature.com/nature/journal/v461/n7266/full/461881a.html

KAUST - the universtiy in the desert (and in a dictatorship like kingdom):
http://www.sciencemag.org/cgi/content/full/326/5951/354?rss=1

PLoS Medicine - refocuses and adopts new interesting concepts - from Twitter to PLoS Currents:
http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1000167


Methylation:
An interview with one of founders of "methylation": Adrian Bird
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000667

Nice debate about how methylation patterns are generated:
http://www.nature.com/nrg/journal/v10/n11/full/nrg2651.html

RNA:
Three way junctions in RNA - found in many RNA structures:
http://rnajournal.cshlp.org/content/15/11/1949.short?rss=1


Biology and Chemistry:
Nature Chemical Biology about the downsides of an reductionist apporach - Cells are more than the simple sum of it's part (systems biology?)
http://www.nature.com/nchembio/journal/v5/n11/full/nchembio.258.html
http://www.nature.com/nchembio/journal/v5/n11/full/nchembio.241.html

RNA and Chromatin structure control a range of biological processes - an overview:
http://www.nature.com/nrg/journal/v10/n11/full/nrg2692.html

Structual Biology:
Oberving biology in atomic resolution in real time - cool:
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCV-4XGTJ7J-1&_user=1676895&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000054205&_version=1&_urlVersion=0&_userid=1676895&md5=635a71eaba1f693b8a8e71044c882860

Bioinformatics:
A new twist for determining possible drug targets based on kinetic network models:
http://www.biomedcentral.com/1471-2105/10/344

Know the CPU architecture and make BLAST faster:
http://www.biomedcentral.com/1471-2105/10/329

Riboswitch detection on sequence level:
http://www.biomedcentral.com/1471-2105/10/325

Glad to know that the PSI is advancing

PSI (Protein Structure initiative) is an initiative that aims to shed light on proteins with roughly unknown function.

There is a new videocast available from a recent meeting:
http://videocast.nih.gov/PastEvents.asp?c=4

Want to know more? Here's the FAQ:
http://www.nigms.nih.gov/Initiatives/PSI/psi_biology/psibiology_faqs.htm

And the corresponding press report is at:
http://kb.psi-structuralgenomics.org/update/2009/10/full/nw_psisgkb.2009.47.html